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The journal «ONCOSURGERY» 2014, Vol.6, No 1

Magnetic-laser therapy for prevention of radiation-induced reactions in gynecological cancer patients

Filonenko EV1, Demidova LV1, Boiko AV1, Urlova AN1, Ivanova-Radkevich VI2

1) PA Herzen Moscow Cancer Research Institute,
2) Peoples’ Freindship University of Russia,
Moscow, Russia
Contact: Urlona Antonina Nicolaevna, e-mail:

Radiotherapy as definitive modality or part of combined modality therapy has an important role for treatment of patients with cervical cancer. The rate of radiation-induced complications varies from 1.2 to 18% (radiation cystitis, proctitis and enterocolitis), in some instances requires interruption of treatment course or causes the failure to meet terms between modalities of combined treatment, which compromise oncological results. Recently, low-level laser therapy has been used to prevent and reveal acute and late radiation-induced reactions in intestine and bladder.

Material and methods. In P.A. Herzen MCRI the technique of magnetic-laser therapy for prevention of radiation induced reactions in cancer patients was developed. Magnetic-laser therapy in the course of radiation was performed in 48 patients with cervical cancer. The age of patients accounted from 25 to 78 y.o. The mean age was 52. According to extent of tumor patients had stage IВ (Т1вNoMo) – IV (Т3вN1M1) of cervical cancer. For morphological structure squamous cell cancer with different differentiation was the most common – in 45 (93.7 %) patients.

Results. Twenty seven patients of 48 had no complications. In the course of radiotherapy grade I radiation proctitis occurred in patients received dose of 38 Gy, grade II radiation proctitis was in patients with dose of 39.3 Gy. Grade I radiation cystitis occurred in patients received dose of 39.4 Gy, grade II radiation cystitis was in patients with dose of 41.3 Gy. Grade I radiation enterocolitis occurred in patients received dose of 33.7 Gy, grade II radiation enterocolitis was in patients with dose of 43.6 Gy, grade III was diagnosed in one patient who received dose of 48 Gy.

Conclusion. Thus, low-level laser therapy in patients with cervical cancer decreases rate and severity of radiation-induced reactions, allows to perform radiotherapy in scheduled time and to improve quality of life in this group of patients.

KEY WORDS: cervical cancer, radiotherapy, radiation-induced reaction, low-level laser radiation.


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