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The journal «ONCOSURGERY» 2013, Vol.5, No 3

Desmoid Tumor of the Breast

Zorka Inic1, Gordana Pupic1, Marko Buta1, Merima Oruci1, Radan Dzodic1,2

1) Institute for Oncology and Radiology of Serbia,
2) University of Belgrade School of Medicine,
Belgrade, Serbia
Contact: Zorka Inic, e-mail:

The case of mammary desmoid tumor is represented in the article.

Material and methods. The female patient, 38 y.o., had a tumor in the lower medial quadrant, in the inframammary sulcus of the left breast, with the infiltration of soft tissue and enlarged lymph nodes in the left axilla. Clinically and radiographically tumor was highly suspected to be carcinoma.

Results. Data from clinical examination, ultrasonography, mammography and cytological analysis are described. The surgery required a broad partial resection of the lower medial quadrant of the left breast and a large part of the pectoralis major muscle was resected. Frozen section examination was non conclusive.

In this case study, histopathological analysis did not show breast carcinoma and possible involvement of the skin and the pectoralis major muscle and confirmed the fibromatosis without infiltration of the skin and muscle tissue. This led to a broad partial resection of breast tissue with clear resection margins. Due to the presence of suspicious, clinically enlarged lymph nodes in the levels I and II of left axillae, axillary clearance was performed together in addition to SLNB. Definite hystopathology showed follicular hyperplasia of axillary lymph nodes.

Conclusion. Fibromatosis of the breast is an extremely rare entity. The standard primary treatment method is surgical, when it is possible. The aim is to achieve clear resection margins with the preserved function and cosmetic effect. Surgical principles entail en bloc resection. The operation range varies from a broad tumorectomy to radical mastectomy with the removal of pectoral fascia and pectoral musculature. We should not have done axillary clearance before getting histopathology report of sentinel lymph node, despite presence of clinically suspicious tumor in the breast and enlarged axillary lymph nodes.

KEY WORDS: mammary desmoid tumor, fibromatosis, sentinel lymph node.

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