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The journal «ONCOSURGERY» 2014, Vol.6, No 1

Invasive sonography in diagnosis of pancreatic tumor: technique and results

Stepanov SO, Kazakevich VI, Sidorov DV, Prozorova EV

PA Herzen Moscow Cancer Research Institute, Department of ultrasound diagnostics, Moscow, Russia
Contact: Prozorova Elina Vladimirovna, e-mail:

Objective: to assess diagnostic accuracy and safety of transabdominal ultrasound-guided biopsies in diagnosis of pancreatic tumors.

Material and methods: we performed study of 52 biopsies with US guidance in patients admitted for surgical treatment in the department of abdominal surgery in PA Herzen MCRI in the period from 2011 to 2013. The biopsies were made by 18G and 20G biopsy needles. Obtained specimen was sent for routine histological or cytological analysis. We assessed diagnostic accuracy and complication rates. All patients underwent surgical treatment within 2 or 74 days (average – 31±7.4 days) after biopsy. Post-manipulation complications and peritoneal dissemination were assessed intraoperatively.

Results: The accuracy of pancreatic tumor biopsies accounted for. Repeated biopsy was required in 2 patients (3%). In 50 patients morphological diagnosis was determined after first biopsy. Biopsy material was sent for histological study in 40 (80%) patients, for cytological study in 10 (20%) patients. Nondiagnostic material was obtained only in 1 patient. The complication rate accounted 1.9% (1 patient). Peritoneal dissemination rate was 7.6% (4 patients).

Conclusion: pancreatic tumor biopsies with US guidance is highly effective and safe method for diagnosis of pancreatic lesions.

KEY WORDS: pancreatic cancer, pancreatic neuroendocrine tumor, ultrasound investigation, biopsy.


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